{"created":"2023-06-20T15:24:31.979551+00:00","id":917,"links":{},"metadata":{"_buckets":{"deposit":"ecec6673-5c5e-4127-86ca-099586767456"},"_deposit":{"created_by":4,"id":"917","owners":[4],"pid":{"revision_id":0,"type":"depid","value":"917"},"status":"published"},"_oai":{"id":"oai:nagoya-wu.repo.nii.ac.jp:00000917","sets":["70:85"]},"author_link":["5681","5685","5684","5682","5686","5683"],"item_1_biblio_info_14":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1977-03-15","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"139","bibliographicPageStart":"133","bibliographicVolumeNumber":"23","bibliographic_titles":[{"bibliographic_title":"名古屋女子大学紀要"},{"bibliographic_title":"Journal of the Nagoya Women's College","bibliographic_titleLang":"en"}]}]},"item_1_creator_6":{"attribute_name":"著者名(日)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"八木, 滋子"}],"nameIdentifiers":[{"nameIdentifier":"5681","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"阿多, 実茂"}],"nameIdentifiers":[{"nameIdentifier":"5682","nameIdentifierScheme":"WEKO"}]}]},"item_1_creator_7":{"attribute_name":"著者名よみ","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"ヤギ, シゲコ"}],"nameIdentifiers":[{"nameIdentifier":"5683","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"アタ, サネシゲ"}],"nameIdentifiers":[{"nameIdentifier":"5684","nameIdentifierScheme":"WEKO"}]}]},"item_1_creator_8":{"attribute_name":"著者名(英)","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"YAGI, Shigeko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"5685","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"ATA, Saneshige","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"5686","nameIdentifierScheme":"WEKO"}]}]},"item_1_description_1":{"attribute_name":"ページ属性","attribute_value_mlt":[{"subitem_description":"P(論文)","subitem_description_type":"Other"}]},"item_1_description_11":{"attribute_name":"抄録(日)","attribute_value_mlt":[{"subitem_description":"\"1.BAY-b5097の血中濃度測定はC-pt.-4を試験菌とし,半合成培地Bを使用してBioassay比濁法により行なった. 2.標準発育阻止曲線より得られる測定可性欲は0.032～0.5μg/ml 3.正常ウナギにおけるBAY-b 5997血中濃度は投与1時間後に最高値に達し,5時間まで高濃度が続き,以後減少して24時間以降はほとんど検出されない. 4.C.-a.-5333感染ウサギにおけるBAY-b血中濃度は,正常ウサギのそれより低いが,推移は同じで1～2時間後に最高値となり,以下3～6時間維持される.24時間以後はほとんど検出されない. 5.ヒト血中濃度においては,164検体中0.032μg/ml以下が132検体,0.032～0.5μg/mlが24検体,0.5μg/ml以上7検体であった. 6.5-FCの血中濃度測定はMIC 0.016g/mlのC.pt-4を試験菌とし,BYMAを使用してカップ法により行なった. 7.標準発育阻止曲線より得られる5-FC測定可能域は2.5～100μg/ml. 8.正常ウサギにおける5-FC血中濃度は,経口投与後1時間で最高位に達し,3～5時間がピークで12時間では最高値の1/3以下,24時間以後はほとんど検出されない.最後にこの実験を行なうにあたり当研究施設の近藤譲,神戸俊夫両助手および森友世,末吉真知子両技官に御協力をいただきました.御高礼申上げます.\"","subitem_description_type":"Other"}]},"item_1_source_id_13":{"attribute_name":"雑誌書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN00179986","subitem_source_identifier_type":"NCID"}]},"item_1_text_10":{"attribute_name":"著者所属(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"\"Institute of Medical Mycology, School of Medicine, Nagoya University"},{"subitem_text_language":"en","subitem_text_value":"NAGOYA WOMEN'S COLLEGE\""}]},"item_1_text_2":{"attribute_name":"記事種別(日)","attribute_value_mlt":[{"subitem_text_value":"論文"}]},"item_1_text_9":{"attribute_name":"著者所属(日)","attribute_value_mlt":[{"subitem_text_value":"名古屋大学医学部医真菌研究施設"},{"subitem_text_value":"名古屋女子大学"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"1977-03-15"}],"displaytype":"detail","filename":"KJ00000684291.pdf","filesize":[{"value":"427.8 kB"}],"format":"application/pdf","license_note":"BY-NC-ND","licensetype":"license_note","mimetype":"application/pdf","url":{"url":"https://nagoya-wu.repo.nii.ac.jp/record/917/files/KJ00000684291.pdf"},"version_id":"1d761a7d-c43f-4df4-9161-2bdc07dc9f7b"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"新抗真菌剤の血中濃度測定に関する基礎的研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"新抗真菌剤の血中濃度測定に関する基礎的研究"},{"subitem_title":"Study on Serum Concentration Assay In Vitro for New Antifungal Drugs","subitem_title_language":"en"}]},"item_type_id":"1","owner":"4","path":["85"],"pubdate":{"attribute_name":"公開日","attribute_value":"1977-03-15"},"publish_date":"1977-03-15","publish_status":"0","recid":"917","relation_version_is_last":true,"title":["新抗真菌剤の血中濃度測定に関する基礎的研究"],"weko_creator_id":"4","weko_shared_id":4},"updated":"2023-06-20T16:14:14.794271+00:00"}